Current immunotherapy approaches often result in partial immunity that predisposes the patient to a risk of reinfection or serious toxicity issues. In Singh Lab, we focus on developing nano-engineered technologies to modulate immune cells and program them for cancer immunotherapy.

To that end, we have engineered a self-assembly protein-biomaterial nanogel system for inducing robust immunity at low protein doses. Our more recently funded project with Prof. Brian Rudd at Cornell Immunology focuses on developing nanoneedles for cancer immunotherapy.

Purified Tumor Antigen

cancer immunotherapynanoneedles